What is a subendocardial infarction?
Subendocardial infarction was defined as typical chest apin (greater than 15 minutes), serum enzyme elevation and persistent (greater than 48 hours) new T wave inversion and/or S-T segment depression in the absence of new pathologic Q waves.
What causes subendocardial infarction?
Regional infarcts are due to lack of blood flow that occurs when an epicardial artery is blocked by atheroma or thrombus, or other obstructions. Global subendocardial infarcts occur when there is lack of oxygenation despite circulation—for example, when there is a respiratory arrest followed by prolonged hypoxemia.
Where is subendocardial infarction?
A subendocardial infarct results in necrosis exclusively inolving the innermost aspect of the myocardium. Usually a subendocardial infarct is the result of a partially occluded epicardial coronary artery (i.e. NSTEMI).
What is the difference between a transmural and subendocardial infarction?
The transmural type usually consisted of yellowish-brown coagulation necrosis in the center of an infarcted focus and coagulative myocytolysis at the marginal zone. The subendocardial type was characterized by coagulative myocytolysis throughout the entire focus.
What causes subendo Cardial zone myocardial infarction?
Subendocardial: these infarcts involve inner one third to one half of ventricular wall as subendo cardial zone is less perfused area of myocardial zone. The infarcts are caused by hypoperfusion of myocardium and not by coronary occlusion.
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What is the definition of myocardial infarction?
3. MYOCARDIAL INFARCTION MI is defined as a diseased condition which is caused by reduced blood flow in a coronary artery due to atherosclerosis & occlusion of an artery by an embolus or thrombus. MI or heart attack is the irreversible damage of myocardial tissue caused by prolonged ischaemia & hypoxia.
What happens at the periphery of an infarct?
At periphery of an infarct, inflammatory reaction is noted. Initially neutrophils predominate ,later macrophages and fibroblasts appear. Eventually, necrotic area is replaced by fibrous scar tissue, may show dystrophic calcification.