What are the symptoms of ectodermal dysplasia?
Symptoms
- Abnormal nails.
- Abnormal or missing teeth, or fewer than normal number of teeth.
- Cleft lip.
- Decreased skin color (pigment)
- Large forehead.
- Low nasal bridge.
- Thin, sparse hair.
- Learning disabilities.
What is ectodermal dysplasia caused by?
Ectodermal dysplasias are genetic disorders, which means that they can be passed on from affected people to their children. They are caused by mutations in various genes ; the mutations may be inherited from a parent, or normal genes may become mutated at the time of egg or sperm formation, or after fertilization.
How is ectodermal dysplasia treated?
Treatment of hypohidrotic ectodermal dysplasia may include special hair care formulas or wigs, measures to prevent overheating, removal of ear and nose concretions, and dental evaluations and treatment (e.g., restorations, dental implants, or dentures).
When is ectodermal dysplasia diagnosed?
Ectodermal dysplasia is diagnosed by physical examination. Some children are diagnosed at birth, but milder forms of the disorder may go undetected until symptoms begin to affect the child’s daily life or development.
What does ectodermal dysplasia affect?
Ectodermal dysplasias are a diverse group of genetic disorders that involve defects of the hair, nails, teeth, skin and glands. Other parts of the body, such as the eyes or throat, may be affected as well.
Is ectodermal dysplasia rare?
All of the 180+ different types of ectodermal dysplasias are considered “rare” because they affect less than 200,000 people in the United States. But some of the syndromes are much more rare than others.
What are the causes of missing teeth in ectodermal disorder?
The congenital missing of teeth is usually bilateral. Anodontia or hypodontia may be associated with other ectodermal disturbances, such as anhidrosis, asteatosis, hypotrichosis, and salivary glands defects.
How many syndromes are there in ectodermal dysplasia?
Ectodermal dysplasia. Ectodermal dysplasia (ED) is not a single disorder but a group of syndromes all deriving from abnormalities of the ectodermal structures. More than 150 different syndromes have been identified. Despite some of the syndromes having different genetic causes, the symptoms are sometimes very similar.
What are the tissues of the ectoderm that are affected?
Ectodermal dysplasia (ED) is one of the rare hereditary disorders that demonstrate primary developmental defects of two or more tissues derived from the ectoderm. Primarily affected tissues are the skin, hair, nails, eccrine glands, and teeth.
When do you need dentures for Ectodermal dysplasia?
The development of tooth buds frequently results in congenitally absent teeth (in many cases a lack of a permanent set) and/or in the growth of teeth that are peg-shaped or pointed. The enamel may also be defective. Cosmetic dental treatment is almost always necessary and children may need dentures as early as two years of age.