Can colchicine be crushed?

Can colchicine be crushed?

General. You can take colchicine with or without food. Take this drug at the time(s) recommended by your doctor. You can cut or crush the tablet (Colcrys).

What type of chemical is colchicine?

Colchicine is an alkaloid extracted from the colchicum autumnale plant, having molecular formula C22H25NO6, and consists of three rings. Many studies are concerned with structural changes in order to increase their pharmacological effectiveness and reduce the side effects of toxicity arising from it.

Is colchicine a polar molecule?

Colchicine is a plant alkaloid that is widely used for treatment of gout….3.1Computed Properties.

Property Name Property Value Reference
Topological Polar Surface Area 83.1 Ų Computed by Cactvs 3.4.8.18 (PubChem release 2021.05.07)

Can Valtrex be crushed?

You may take valacyclovir with or without food. Swallow each tablet whole with water. Do not chew it.

Can you crush fluconazole?

General. You can take fluconazole with or without food. You can cut or crush the tablet.

Is colchicine soluble in water?

Product Details

Formula: C22H25NO6
Solubility: Soluble in DMSO (14mg/ml), 100% ethanol (7mg/ml), water (7mg/ml) or dimethylformamide (12mg/ml).
Shipping: Ambient
Long Term Storage: +4°C
Handling: Protect from light and moisture.

Is colchicine a controlled substance?

Colchicine is used in the treatment of gout, acute; gout, prophylaxis; familial mediterranean fever and belongs to the drug class antigout agents. Risk cannot be ruled out during pregnancy. Colchicine colchicine 0.6 mg is not a controlled substance under the Controlled Substances Act (CSA).

Can Valtrex be dissolved in water?

Valacyclovir hydrochloride is a white to off-white powder with the molecular formula C13H20N6O4•HCl and a molecular weight of 360.80. The maximum solubility in water at 25°C is 174 mg/mL.

Is it OK to crush acyclovir?

Take this drug at the time(s) recommended by your doctor. You can take acyclovir with or without food. Taking it with food may help reduce upset stomach. Do not cut or crush this medication.