What is triglyceride-rich lipoprotein metabolism?
Triglyceride-rich lipoproteins come from 2 sources, often described as the endogenous and exogenous pathways. In the exogenous pathway, dietary fats (triglycerides) are hydrolyzed to free fatty acids (FFAs) and monoglycerides and are absorbed, with cholesterol, by intestinal cells.
What is the metabolism of lipoprotein?
lipoprotein metabolism is the process by which hydrophobic lipids, namely triglycerides and cholesterol, are transported within the interstitial fluid and plasma.
Are lipoproteins triglycerides?
Lipoproteins are complex particles that have a central hydrophobic core of non-polar lipids, primarily cholesterol esters and triglycerides. This hydrophobic core is surrounded by a hydrophilic membrane consisting of phospholipids, free cholesterol, and apolipoproteins (Figure 1).
What is the main function of triglyceride?
Triglycerides store unused calories and provide your body with energy. Cholesterol is used to build cells and certain hormones.
What are the sources of triglycerides?
They come from foods, especially butter, oils, and other fats you eat. Triglycerides also come from extra calories. These are the calories that you eat, but your body does not need right away. Your body changes these extra calories into triglycerides and stores them in fat cells.
How are triglycerides transported?
Triglycerides and cholesteryl esters are transported in the core of plasma lipoproteins. The intestine secretes dietary fat in chylomicrons, lipoproteins that transport triglyceride to tissues for storage. Dietary cholesterol is transported to the liver by chylomicron remnants which are formed from chylomicrons.
Which lipoprotein is rich in triglycerides?
The lipoproteins that predominantly transport triglycerides are chylomicrons and VLDL. Chylomicrons are large triglyceride-rich particles secreted by the intestines following ingestion of dietary fat.
Which lipoprotein contains the most triglycerides?
Chylomicrons
Chylomicrons – these are the largest and least dense of the lipoproteins, with the highest triglyceride content. They consist of a protein component synthesized in the liver, which wraps around diet-derived cholesterol and fats.
What are the 5 groups of lipoproteins?
Plasma lipoproteins are separated by hydrated density; electrophretic mobility; size; and their relative content of cholesterol, triglycerides, and protein into five major classes: chylomicrons, very-low-density lipoproteins (VLDL), intermediate-density lipoproteins (IDL), low-density lipoproteins (LDL), and high- …
What are the major functions of fatty acids and triglycerides in the body?
What are the major functions of fatty acids and triglycerides in the body? To insulate and protect the body, to aid in transport of fat-soluble vitamins, and to provide energy.