What is a adenovirus infection?
Adenoviruses are common viruses that cause a range of illness. They can cause cold-like symptoms, fever, sore throat, bronchitis, pneumonia, diarrhea, and pink eye (conjunctivitis). You can get an adenovirus infection at any age.
What causes adenovirus?
Adenovirus can spread through droplets when someone with an infection coughs or sneezes. Fecal material (poop) can spread the infection via contaminated water, dirty diapers, and poor hand washing. Outbreaks of pharyngoconjunctival fever at summer camps are linked to contaminated water in swimming pools and lakes.
What type of virus is the adenovirus?
Adenoviruses are medium-sized (90-100 nm), non-enveloped icosohedral viruses with double-stranded DNA. More than 50 types of immunologically distinct adenoviruses can cause infections in humans.
What is rhinovirus and adenovirus?
About 50% of common colds are caused by some kind of rhinovirus. (About 10% of common colds are due to infection with a different type of virus, such as adenovirus, while the cause in 40% of cases is unknown.) Rhinoviruses thrive in the upper respiratory tract, particularly the nose and throat.
Where is adenovirus most common?
Most adenovirus infections occur among young children (under 5 years of age). Adults who are in closed or crowded environments, such as in dormitories, military quarters, nursing homes, or hospitals are also at higher risk.
What is human adenovirus vaccine?
In this vaccine, a modified version of a chimpanzee adenovirus (ChAdOx1) is used which can enter human cells but not replicate inside. A gene for the coronavirus vaccine was added into the adenovirus DNA, allowing the vaccine to target the spike proteins that SARS-CoV-2 uses to enter human cells.
Where are adenovirus found?
Adenoviruses are a group of common viruses that infect the lining of your eyes, airways and lungs, intestines, urinary tract, and nervous system.
How does adenovirus affect the body?
Common symptoms include cough, fever, fast breathing, wheezing and sore throat. Adenovirus can also cause diarrhea, eye infections (conjunctivitis or pink eye) and even urinary tract infection. More rarely, it can be associated with liver (hepatitis), brain (encephalitis), and/or heart (myocarditis) problems.
Is adenovirus an RNA virus?
Adenovirus infection, as is the case with other viruses, could lead to the production of double-stranded RNA (dsRNA) through symmetrical transcription of the viral genome.
What cells does adenovirus infect?
Currently, about 110 human adenovirus (HAdV) types and genotypes are known and classified into seven species (A-G). AdVs infect the respiratory organs, the eyes, the kidney, the gastrointestinal tract and blood cells. On a population scale, AdVs emerge unpredictable, and can cause human epidemics.
How is Adenovirus diagnosed?
Diagnosis of adenovirus typically starts with a clinical evaluation of a person’s symptoms. Doctors will sometimes use adenovirus laboratory diagnosis testing like blood or stool cultures, nasal swabs, or chest X-rays to confirm an adenovirus diagnosis.
How do adenoviruses replicate?
Adenovirus replicates inside the nucleus (Fig. 17.9). By the DNA replication process, the adenovirus multiplication cycle is separated into two phases i.e., an early phase and a late phase. In both phases a primary transcript is formed which is spliced to produce monocistronic mRNA which is compatible with the host’s ribosome.
What is the adenovirus virus?
Definition of adenovirus. : any of a family (Adenoviridae) of double-stranded DNA viruses originally identified in human adenoid tissue, causing infections of the respiratory system, conjunctiva, and gastrointestinal tract, and including some capable of inducing malignant tumors in experimental animals.
How do adenoviruses work?
Entry of adenoviruses into the host cell involves two sets of interactions between the virus and the host cell. Most of the action occurs at the vertices. Entry into the host cell is initiated by the knob domain of the fiber protein binding to the cell receptor.
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