What are some examples of GnRH agonists?
GnRH agonists that have been marketed and are available for medical use include buserelin, gonadorelin, goserelin, histrelin, leuprorelin, nafarelin, and triptorelin.
What drug induces the release of gonadotropins?
Gonadotropin-releasing hormone (GnRH) analogues produce a hypogonadotrophic-hypogonadic state by downregulation of the pituitary gland. Goserelin and leuprolide acetate are commonly used agonists. Normal menstrual cycles rely on pulsatile delivery of GnRH to the pituitary.
What is GnRH medication?
Gonadotropin releasing hormone agonists (GnRH) are a type of medication that suppresses ovulation by stopping the production of estrogen and progesterone. In order for this axis to function properly and result in ovulation, GnRH has to be released in a pulsatile fashion.
Is Lupron and Decapeptyl the same?
Different countries have different drug names. In either 3mg or 3.75mg form, they sit on pharmacy shelves as Lupron, Decapeptyl, Prostap SR, Diphereline, Enanton, Gonapeptyl or Procren.
What are Zoladex injections?
Zoladex contains a medicine called goserelin. This belongs to a group of medicines called ‘LHRH analogues’. In men, Zoladex is used to treat prostate cancer. It works by reducing the amount of ‘testosterone’ (a hormone) that is produced by your body.
What does a GnRH antagonist do?
A substance that blocks the pituitary gland from making hormones called follicle-stimulating hormone (FSH) and luteinizing hormone (LH). In men, this causes the testicles to stop making testosterone. In women, this causes the ovaries to stop making estrogen and progesterone.
What are gonadotropin injections?
Gonadotropins are injectable hormones used to treat infertility. These medications, including Follistim, Menopur, Bravelle and Gonal-F, all contain an active form of the FSH, the main hormone responsible for producing mature eggs in the ovaries.
Is Lupron a gonadotropin-releasing hormone agonist?
Leuprolide injection (Lupron Depot) is also used with other medication to treat anemia (a lower than normal number of red blood cells) caused by uterine fibroids (noncancerous growths in the uterus). Leuprolide injection is in a class of medications called gonadotropin-releasing hormone (GnRH) agonists.
Is Lupron a GnRH?
Is triptorelin the same as leuprolide?
Both treatments were well tolerated. Conclusion: Triptorelin reduced testosterone concentrations less rapidly, but maintained castration as effectively as leuprolide. There was no evidence that the slower onset of castration caused deleterious effects.