Is polyethylene glycol water-soluble?
Water
Polyethylene glycol/Soluble in
Is polyethylene glycol an organic solvent?
Effect of polyethylene glycol (PEG) on protein solubility has been primarily ascribed to its large hydrodynamic size and thereby molecular crowding effect. However, PEG also shows characteristics of organic solvents.
Why is polyethylene glycol water-soluble?
The OH, at the terminus make it hydrophilic. More over ether oxygen can hydrogen bond with water. This makes it stretch out and make it soluble. Poly(propylene glycol) is much less hydrophilic, and this leads to variety of PEG-PPG polymeric surfactants.
What are the properties of polyethylene glycol?
Characteristics of polyethylene glycol It is non-toxic, colorless, inert, odorless, and non-volatile. Also, it is incredibly soluble in water, and organic solvents such as benzene, carbon tetrachloride, and chloroform.
How does polyethylene glycol dissolve in water?
PEG can be dissolved in warm water at 80-90 °C with no adverse effects. Sterile filtration of the solution is recommended using a 0.45 µm filter, initially. Although autoclaving of PEG in saline solutions has been reported,4 it is not recommended.
Is polyethylene glycol soluble in ethanol?
PEG is soluble in water, methanol, ethanol, acetonitrile, benzene, and dichloromethane, and is insoluble in diethyl ether and hexane.
What is the role of polyethylene glycol?
Polyethylene glycol 3350 is used to treat occasional constipation. Polyethylene glycol 3350 is in a class of medications called osmotic laxatives. It works by causing water to be retained with the stool. This increases the number of bowel movements and softens the stool so it is easier to pass.
Is polyethylene glycol polar or nonpolar?
However, PEG is a relatively nonpolar molecule that interacts favorably with the nonpolar surfaces exposed when a macromolecule unfolds, and the net effect is that PEG destabilizes folded proteins (1, 2).
How do you make polyethylene glycol solution?
50% PEG
- Measure out 25 grams of PEG 3500 into a 100 mL glass bottle.
- Add 25 mL water and vortex well. Let rest for 10 min.
- Add water to 50 mL total volume. Vortex again and let rest until solution looks clear.
- Sterilize by autoclave on liquid 20 minute cycle or sterile filter into a new bottle.