How long is NS1 positive?
Positive test for DENV may mean that NS1 antigen is typically detectable within 1 to 2 days following infection and up to 9 days following symptom onset. NS1 antigen may also be detectable during secondary dengue virus infection, but for a shorter duration of time (1-4 days following symptom onset).
What is the normal range of dengue NS1 antigen?
An NS1 Ag level varies from 0.5-2 μg/ml in acute-phase serum samples, to less than 0.04 μg/ml in convalescent phase serum [11].
What is normal value of NS1 antigen?
The positive predictive value of a NS1 antigen positivity between days 5-6 of illness and development of severe clinical disease was 63.6 (95% confidence interval 49.6 to 76.1) and the negative predictive value was 63.2 (95% confidence interval 49.3 to 75.5).
What is difference between dengue NS1 and IgM?
NS1 antigen is generally found during Day 1 and up to Day 9 after onset of fever. The detection of anti-NS1 is inhibited if anti-NS1 antibodies produced. Whereas IgM become detectable by Day 3 to Day 5 after onset of illness in primary dengue and by Day 1 to Day 2 after onset of illness in secondary infections.
What happens if dengue NS1 antigen is positive?
A positive NS1 test result confirms dengue virus infection without providing serotype information. A negative NS1 test result does not rule out infection. People with negative NS1 results should be tested for the presence of dengue IgM antibodies to determine possible recent dengue exposure.
What if NS1 antigen is positive?
How can I check my dengue NS1 report?
Dengue IgG & IgM serology assays should be performed on follow up samples after 5-7 days of onset of fever, to confirm dengue infection. Note: Recommended to do NS1 Antigen by ELISA in the first 5 days of fever. After 7-10 days of continuous fever, the recommended test is Dengue fever antibodies IgG & IgM by ELISA.
How do you treat dengue NS1 positive?
The NS1 antigen test is the most effective for early diagnosis of dengue infection. The main focus of treatment is to ensure that the patient gets adequate hydration. Acetaminophen (paracetamol) is used to manage the fever. If the symptoms are treated properly, the patient should recover in around two weeks.
What if dengue IgM is positive?
Positive IgM and IgG tests for dengue antibodies detected in an initial blood sample mean that it is likely that the person became infected with dengue virus within recent weeks. IgM antibody tests can be positive if a person has been infected with a similar virus, such as chikungunya (called cross-reaction).
What is the normal range for a dengue NS1 test?
What is the normal range for a dengue NS1 test? The NS1 antigen can usually be detected in blood within 1-2 days after the symptoms and up to a period of 7 days. The negative test results indicate that the antigen has not been detected whereas a positive result indicates the presence of dengue.
What does a negative dengue test result mean?
The negative test results indicate that the antigen has not been detected whereas a positive result indicates the presence of dengue. Results can come negative if the specimen was collected after 7 days following the symptom onset. What do the results mean?
How long does it take to get a positive NS1 test?
The NS1 antigen can usually be detected in blood within 1-2 days after the symptoms and up to a period of 7 days. The negative test results indicate that the antigen has not been detected whereas a positive result indicates the presence of dengue.
When do IgM results come back for dengue?
IgM levels are variable, but generally are positive starting 4-5 days after onset of symptoms and continuing for approximately 12 weeks post symptom onset, but may persist longer. What is the test? The dengue MAC-ELISA is used for the qualitative detection of dengue virus IgM antibodies.