What is the purpose of thallium?
A thallium (or cardiolite) scan uses a radioactive tracer to see how much blood is reaching different parts of your heart. These tests are the more common forms of tests called nuclear medicine scans.
What is the energy of thallium-201?
Thallium-201 is a cyclotron-produced radionuclide that decays by electron capture, with a half-life of about 73 hours. On decay, the major emissions are characteristic x-rays of the daughter product, mercury-201 (201Hg), with an energy range of 69 to 81 keV.
What is thallium-201 contrast material?
Thallium-201 (Th-201) is a radiopharmaceutical used for scintigraphy, primarily of the myocardium. The element thallium is treated by the body as an analog of potassium; it is produced in a cyclotron by bombarding thallium-203 with protons.
Can Thallium-201 be used to detect heart disease?
Background. Thallium-201 myocardial perfusion image (MPI) is commonly used to detect coronary artery disease in patients with chest pain.
How is Thallium 201 used in medicine?
Thallium-201 is a radiopharmaceutical agent used in the diagnosis of coronary artery disease and parathyroid hyperactivity. Other useful applications for a thallium-201 scan, like tumor diagnosis and olfacto-scintigraphy, are being explored and have shown promising results in various studies.
Which is better stress thallium vs angiography?
When compared with the EKG stress test, thallium stress imaging was superior in sensitivity (80% vs 68%), specificity (84% vs 49%), accuracy (81% vs 62%), positive predictive value, (92% vs 75%), and negative predictive value (65% vs 45%) in this group, with 71% prevalence of angiographically significant coronary …
How does thallium chloride 201 enter the body?
Tl-201 has 73 h of physical half-life (t ½). It is produced in the cyclotron. It is administered intravenously to the patients as thallous chloride. After intravenous injection, about 88% is cleared from the blood after the first circulation.
Is Thallium-201 natural or synthetic?
Thallium is a chemical element with the symbol Tl and atomic number 81. It is a gray post-transition metal that is not found free in nature.
When is Thallium-201 used?
Thallium-201 is a radiopharmaceutical agent used in the diagnosis of coronary artery disease and parathyroid hyperactivity.
Is Thallium-201 toxic?
The radioisotope thallium-201 (as the soluble chloride TlCl) is used in small amounts as an agent in a nuclear medicine scan, during one type of nuclear cardiac stress test. Soluble thallium salts (many of which are nearly tasteless) are highly toxic, and they were historically used in rat poisons and insecticides.
Where is Thallium-201 made?
Thallium-201 production at the National Medical Cyclotron|INIS.
What radiation does Thallium-201?
Tl-201 emits emitting mainly X-rays of energy 67–82 keV (88% abundance) and gamma photons of 135 and 167 keV (12% abundance). X or gamma rays could not be visible.