What does a high platelet count mean in a child?
A high platelet count is 400,000 (400 × 109/L) or above. A higher-than-normal number of platelets is called thrombocytosis. It means your body is making too many platelets. Causes may include: A type of anemia in which red blood cells in the blood are destroyed earlier than normal (hemolytic anemia)
What happens if platelets are high?
Thrombocytosis is a condition in which there are an excessive number of platelets in the blood. Platelets are blood cells in plasma that stop bleeding by sticking together to form a clot. Too many platelets can lead to certain conditions, such as stroke, heart attack or a clot in the blood vessels.
Can allergies cause high platelet count?
Conclusions: This observation taken along with our previous results indicates that patients with seasonal allergic rhinitis and asthma symptoms may have an increased circulating platelet activation, yet this phenomenon disappears in the asymptomatic period of the disease.
Can a bacterial infection cause high platelet count?
Any inflammatory process such as bacterial infection, neoplasia, sepsis, multiple trauma, burns, or pancreatitis that elevates serum IL levels (especially IL-6), may increase the circulating platelet count (2,3).
What is a normal platelet count for a child?
In healthy pediatric subjects normal count platelet ranges between 250,000 μL and 450,000 μL. An elevated platelet count greater than 2 SD defines a condition of thrombocytosis.
What is the most common age for childhood leukemia?
ALL is most common in early childhood, peaking between 2 and 5 years of age. AML tends to be more spread out across the childhood years, but it’s slightly more common during the first 2 years of life and during the teenage years.
Can asthma cause elevated platelets?
Patients with asthma have increased levels of platelet-derived mediators, such as PAF-4, β-thromboglobulin (β-TG), RANTES, and thromboxane, both in the peripheral blood and bronchoalveolar lavage (BAL) fluid, suggesting increased levels of platelet activation.
Is a high platelet count good?
The presence of high platelets is rarely associated with a medical emergency. However, in some cases, high platelets may cause blood clotting, bleeding or stroke.
What are the dangers of large platelets?
The most common problem experienced by people with large platelets is increased bleeding. The oversized platelets cannot clot properly and as a result, the patient may bleed freely from even small injuries, develop substantial bruising, and experience internal bleeding that is difficult to stop because…
What medications cause high platelet levels?
Medicines such as Epinephrine (Adrenalin Chloride, EpiPen), Vincristine, Tretinoin, can cause reactive thrombocytosis. ➺ Disorders/Absence of the Spleen: The spleen is responsible for the removal of platelets from the blood. When the spleen is not functioning properly, it can cause an elevated platelet count.
What is the reason for high platelet count?
According to the Mayo Clinic, in primary thrombocythemia, a high blood platelet count is caused by a bone marrow disorder where faulty cells in the bone marrow are producing too many platelets (and the platelets being produced are abnormal). In secondary thrombocytosis, however, the underlying condition is the cause of the high blood platelet count.
What are high platelets a sign of?
While high platelet count can be due to underlying infection, it may also be a sign of a serious bone marrow disorder such as thrombocythemia or primary thrombocytosis, according to the Mayo Clinic.