Is denosumab subcutaneous?
Denosumab injection comes as a solution (liquid) to be injected subcutaneously (under the skin) in your upper arm, upper thigh, or stomach area. It is usually injected by a doctor or nurse in a medical office or clinic. Denosumab injection (Prolia) is usually given once every 6 months.
How do you administer a denosumab injection?
The recommended dose is 60 mg denosumab administered as a single subcutaneous injection once every 6 months into the thigh, abdomen or upper arm. Patients must be adequately supplemented with calcium and vitamin D (see section 4.4).
What Prolia subcutaneous?
Generic Name: denosumab This medication works by slowing bone loss to help maintain strong bones and reduce the risk of broken bones (fractures). Denosumab belongs to a class of drugs called monoclonal antibodies. It prevents certain cells in the body (osteoclasts) from breaking down bone.
Is Prolia given subcutaneously?
The recommended dose of Prolia is 60 mg administered as a single subcutaneous injection once every 6 months. Administer Prolia via subcutaneous injection in the upper arm, the upper thigh, or the abdomen.
What is denosumab subcutaneous used for?
Denosumab is used to treat bone loss (osteoporosis) in people who have a high risk of getting fractures. Osteoporosis causes bones to become thinner and break more easily.
How do you store Prolia at home?
Instruct them to store it in the refrigerator at 36°F to 46°F, in the original carton. Do not freeze or shake it. Prolia® should not be used if it has been at room temperature, 68°F to 77°F, for more than 14 days.
Where is the best place to inject Prolia?
The recommended injection sites for Prolia include: the upper arm OR the upper thigh OR the abdomen. Insert needle and inject all the liquid subcutaneously. Do not administer into muscle or blood vessel. DO NOT put gray needle cap back on needle.
Can you administer Prolia at home?
The current U.S. Prescribing Information states that Prolia® (denosumab) should be administered by a healthcare provider. At this time, self-administration of Prolia® is not approved in the United States.
Can I give myself a Prolia injection?
Prolia is an injection that can be self-administered once every six months for the treatment of osteoporosis. It has been associated with an increased risk of fractures on discontinuation.
Should Prolia be refrigerated?
Prolia® should be stored in a refrigerator (2°C – 8°C). Do not freeze. Keep the pre-filled syringe in the outer carton to protect from light. Prolia® has a shelf life of 36 months and may be stored at room temperature (25°C) for up to 30 days in the original container.
Is Prolia given IM or SQ?
2 DOSAGE AND ADMINISTRATION 2.1 Recommended Dosage Prolia should be administered by a healthcare professional. The recommended dose of Prolia is 60 mg administered as a single subcutaneous injection once every 6 months. Administer Prolia via subcutaneous injection in the upper arm, the upper thigh, or the abdomen.
When to use denosumab subcutaneous advanced patient information?
Uses for denosumab. Denosumab injection is used to treat osteoporosis (thinning of the bones) in women who have an increased risk for fractures after menopause, and osteoporosis in men. It is given when other medicines cannot be used or after other medicines did not work well.
How is denosumab used to treat osteoporosis?
Denosumab injection is used to treat osteoporosis (thinning of the bones) in women who have an increased risk for fractures after menopause, and osteoporosis in men.
Are there any phase 3 studies for denosumab?
Denosumab showed benefit in several phase 3 or 4 studies in PM women with osteoporosis or low bone mineral density (BMD), including the pivotal 3-year double-blind FREEDOM trial and its 7-year open-label extension.
When to use the Prolia subcutaneous syringe for men?
Prolia Syringe. Denosumab is used to treat bone loss (osteoporosis) in women who are at high risk for bone fracture after menopause. It is also used to treat bone loss in men who are at high risk for bone fracture.