What drug is Vastarel?
Trimetazidine is indicated in adults as add-on therapy for the symptomatic treatment of patients with stable angina pectoris who are inadequately controlled by or intolerant to first-line antianginal therapies.
What kind of drug is trimetazidine?
Trimetazidine is a cytoprotective drug that normalizes metabolic disturbances in low-flow ischemia via several—not yet fully understood—mechanisms of action. The best known trimetazidine mechanism of action is its capacity to inhibit β-oxidation of free fatty acid (FFA) [1].
What are antianginal drugs used for?
Antianginal drugs are used to provide immediate relief from symptoms and prevent angina attacks. If your risk of having a heart attack or stroke is high, it should be possible to reduce the risk by using a combination of medication and lifestyle changes.
What is anti ischemic?
Anti-ischaemic therapy Anti-ischaemic drugs decrease myocardial oxygen consumption (by lowering heart rate, blood pressure, myocardial contractility, or ventricular preload) and/or increase myocardial oxygen supply (by coronary vasodilatation).
What is trimetazidine used for?
Trimetazidine belongs to the class of medications called fatty acid oxidation inhibitors. It is used to prevent and treat the symptoms of angina (chest pain). Angina is caused by lack of blood supply and oxygen to your heart.
What is simvastatin used for?
Simvastatin belongs to a group of medicines called statins. It’s used to lower cholesterol if you’ve been diagnosed with high blood cholesterol. It’s also taken to prevent heart disease, including heart attacks and strokes.
Is amlodipine an antianginal?
In comparison with other antianginal drugs, once-daily amlodipine at a dosage range of 5-10 mg demonstrated antianginal activity comparable to thrice-daily diltiazem and once-daily nadolol.
What is the treatment of ischemia?
Treatment for myocardial ischemia involves improving blood flow to the heart muscle. Treatment may include medications, a procedure to open blocked arteries (angioplasty) or bypass surgery. Making heart-healthy lifestyle choices is important in treating and preventing myocardial ischemia.
How are beta blockers anti ischemic?
In particular, beta-blockers are credited with reducing exercise-induced ischemia by decreasing myocardial oxygen demand and possibly by increasing supply through a reduction in extravascular forces [9].
What is the difference between Plavix and clopidogrel?
Plavix and Brilinta are both brand-name drugs. A generic form of Plavix, called clopidogrel, is available for use. However, a generic form of Brilinta is not yet available. A generic drug is an exact copy of a brand-name medication.
Which is the best anti ischemic drug to take?
Nitroglycerin and other nitrates are used for the treatment of acute symptoms. ß-Blockers are first choice for long-term treatment, unless contraindications preclude the use of these drugs.
What are the different names for ischemic stroke?
Medications for Ischemic Stroke. Other names: Cerebrovascular Accident; CVA; Stroke; Stroke, ischemic. About Ischemic Stroke: An Ischemic stroke occurs when a blood vessel that supplies blood to the brain is blocked by a blood clot.
How are antihypertensive drugs used to treat heart disease?
Antihypertensive drug. Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Evidence suggests that reduction of the blood pressure by 5 mmHg can decrease the risk of stroke by 34%, of ischaemic heart disease by 21%, and reduce the likelihood of dementia, heart failure,…
How does ranolazine work in the ischemic heart?
Unlike other anti-ischemic drugs, ranolazine does not decrease the “double product” of heart rate and arterial pressure, a measurement of cardiac mechanical work (Rousseau et al., 2005 ). This implies that ranolazine increases myocardial mechanical efficiency, oxygen supply, or both, in the ischemic heart.