What is the significance of determination of ash value?
Ash values are helpful to determine the quality as well as purity of a crude drug, especially when the drug is present in powdered form. The object of ashing crude drugs is to remove the traces of organic matter which may be interferes in an analytical determination.
What is the significance of acid insoluble ash?
Acid-insoluble ash consists primarily of silica and silicates. This material, when present in the finished paper or paperboard, can have an abrasive effect on punches, knives, slitters and dies which come into contact with paper during finishing operations.
What is water soluble ash?
3.1 water-soluble ash : The part of the total ash dissolved by water under the conditions specified in this International Standard. 3.2 water-insoluble ash : The part of the total ash remaining after treatment with water under the conditions specified in this Inter- national Standard.
What is the importance of determining the total ash and acid insoluble ash content of drugs give their possible composition?
Total ash test gives an estimation about purity and quality of drug. Acid insoluble ash value indicates siliceous impurities. Water soluble ash value gives an estimation of inorganic contents.
How is water soluble ash value determined?
Water- soluble ash: Subtract the weight of insoluble matter from the weight of the ash; the difference in weight represents the water- soluble ash. Calculate the percentage of water- soluble ash with reference to the air dried drug.
What is water soluble extractive value?
% of water soluble extractive = weight of residue/weight of the drug x 100. It is expressed as percent w/w of the air-dried drug.
Is ash water soluble?
Wood ash is not particularly soluble in water, but it’s not quite that simple. It just floats on water. The grey powdery component of the ashes is also a mixture of minerals. It’s about 9% potassium (K) minerals, for example, and these are very soluble in water.
How do you calculate water soluble ash?
What is insoluble ash?
The Acid Insoluble Ash (AIA) content is the proportion of a sample that is not hydrolysed by 72% sulphuric acid and is not subsequently volatilised upon the incineration of this Acid Insoluble Residue.
How do you know if ash is soluble in water?
Water- soluble ash: Subtract the weight of insoluble matter from the weight of the ash; the difference in weight represents the water- soluble ash.
What is acid soluble ash value?
The total ash, acid- nsoluble ash, and water-soluble ash were found to be 19.146 ± 0.237, 2.351 ± 0.223, and 49.216 ± 0.634, respectively; the value of total ash indicates that the inorganic contents of the formulation are below the limits.
Why do we need to check for water content in assay of crude drugs?
Moisture content determination is important, not only to know excess water, but also in conjunction with suitable temperature moisture will lead to the activation of enzymes and gives suitable conditions to the proliferation of living organism.
How is percentage of water soluble ash determined?
The water-soluble ash is used to detect the presence of material exhausted by water. Sulphated ash is done by addition of sulphuric acid in order to get sulphate salts, and the percentage ash is calculated with reference to the air-dried drug. The temperature used for this is above 600°C.
Why is it important to know the ash content of food?
Ash content represents the total mineral content in foods. Determining the ash content may be important for several reasons. It is a part of proximate analysis for nutritional evaluation. Ashing is the first step in preparing a food sample for specific elemental analysis. Because certain foods are high in particular minerals,
What’s the difference between mineral and ash content?
The “ash content” is a measure of the total amount of minerals present within a food, whereas the “mineral content” is a measure of the amount of specific inorganic components present within a food, such as Ca, Na, K and Cl. Determination of the ash and mineral content of foods is important for a number of reasons:
What should the total ash of a crude drug be?
So total ash of a crude drug vary within wide limits for specimens of genuine drug, for example, rhubarb, total ash range from 8 to 40%. In this case, the total ash is useless to detect earthy matter adherent to such a drug. So acid-insoluble ash would be preferable for rhubarb.