What is pleomorphic hyperchromatic nuclei?
The tumors usually present as a nodule on the head or neck. The nuclei of the giant tumor cells are irregularly shaped, hyperchromatic, and 2 to 10 times larger than the nuclei of the surrounding cancer cells. Atypical mitoses may be present.
What is a pleomorphic carcinoma?
Pleomorphic carcinoma (PC) is a rare malignant lung tumor characterized by dual-cell components including spindle or giant cells as well as epithelial cells.
What has a pleomorphic nucleus?
The nuclear pleomorphism observed in anaplastic cells of malignant neoplasms is characterized by nuclei that are highly variable in size and shape. These nuclei exhibit chromatin that appears coarse and clumped.
What are pleomorphic giant cells?
Pleomorphic spindle and giant cell carcinoma (PC) is a rare, poorly differentiated non–small cell lung carcinoma that contains at least 10% spindle and/or giant cells and currently grouped among sarcomatoid carcinomas of the lung by the 2015 World Health Organization classification of lung tumors.
What causes Hyperchromatic nuclei?
A nucleus can become hyperchromatic for different reasons. Non-cancerous cells often become hyperchromatic when they are injured. Pathologists sometimes describe these cells as reactive. Some cancers are also made almost entirely of hyperchromatic cells.
What does enlarged Hyperchromatic nuclei mean?
Enlarged nuclei with hyperchromatic, irregular clumps of chromatin separated with blurred, pale, or clear areas (parachromatin clearing) may occur. These findings may mimic the nuclear changes of malignancy.
What is the meaning of pleomorphic?
Definition of pleomorphic : able to assume different forms : polymorphic pleomorphic bacteria a pleomorphic sarcoma. Other Words from pleomorphic More Example Sentences Learn More About pleomorphic.
What does pleomorphic mean in microbiology?
pleomorphism, the existence of irregular and variant forms in the same species or strain of microorganisms, a condition analogous to polymorphism in higher organisms.
What are giant cells in the lungs?
Pulmonary giant cell carcinoma represents a rare variety of non-small cell lung carcinoma that is characterized by the presence of numerous tumor giant cells and an influx of inflammatory cells that are mostly polymorphonuclear leukocytes admixed with macrophages.
What kind of tumor is a pleomorphic cell tumor?
Pleomorphic cell tumors are characterized by variably sized and shaped cells (often including multinucleate giant cells), with atypical nuclei. They account for approximately 10-15% of soft tissue tumors. Pleomorphism in a soft tissue neoplasm is usually regarded as suggestive of a sarcoma.
Where does pleomorphic lipoma occur in soft tissue?
Spindle cell / pleomorphic lipoma occurs almost exclusively in the subcutaneous tissue of the posterior neck and shoulder area. Less common sites include the face, buccal cavity, scalp, forehead, and orbit. Only a few poorly documented cases have been reported in other locations.
What are the cytological signs of bronchial cell hyperplasia?
Bronchial cell hyperplasia may be seen in the context of asthma, tuberculosis, viral infection or instrumentation. Cytologically, it consists of tight papillary clusters with occasional molding and variable numbers of mucus producing cells – often called Creola bodies.