What are Antilipidemic agents?
Antihyperlipidemic agents promote reduction of lipid levels in the blood. Some antihyperlipidemic agents aim to lower the levels of low-density lipoprotein (LDL) cholesterol, some reduce triglyceride levels, and some help raise the high-density lipoprotein (HDL) cholesterol.
What are Antilipemic drugs?
Antilipemic agents are beneficial in lowering blood cholesterol profiles, thereby possibly reducing the rate of first major vascular events.
What’s the difference between atorvastatin and simvastatin?
Dose for dose, atorvastatin is more potent than simvastatin at blocking the target enzyme, HMGCoA; this effect is overcome by using a higher dose of simvastatin. In controlled dosing studies, simvastatin 40 mg and atorvastatin 10 mg and 20 mg are equally effective.
Which of the following is antihyperlipidemic agent?
The six HMG-CoA reductase inhibitors (statins) are atorvastatin (Lipitor), fluvastatin (Lescol), lovastatin (Mevacor, Altocor), pravastatin (Pravachol), rosuvastatin (Crestor), and simvastatin (Zocor).
Is atorvastatin an antihyperlipidemic?
Atorvastatin [2-(4-fluorophenyl)-β, Δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1Hpyrrole-1-heptanoic acid], an antihyperlipidemic drug, is used along with thrombolytic drugs (aspirin, clopidogrel) in the treatment of myocardial infarction.
Is simvastatin an Antilipidemic?
The present study demonstrates that simvastatin, an antihyperlipidemic drug exhibited broad-spectrum antibacterial activity against important Gram-positive (including methicillin-resistant Staphylococcus aureus (MRSA)) and Gram-negative pathogens (once the barrier imposed by the outer membrane was permeabilized).
Which Antilipemic drug gets rid of bile acids?
Colestyramine removes bile acids from the body by forming insoluble complexes with bile acids in the intestine, which are then excreted in the feces.
What class of drugs are Antilipemic?
The medications for dyslipidemia can be grouped into five categories: fibrates, bile acid resins, hydroxymethylglutaryl co-enzyme A (HMG-CoA) reductase inhibitors (known collectively as statins), proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors and miscellaneous agents.
Is rosuvastatin more effective than atorvastatin?
At the end of the titration-to-goal period, rosuvastatin was significantly more effective than atorvastatin on the primary efficacy measure, reducing LDL-C by 52% compared with 46% in the atorvastatin group (p < 0.0001) (table
What is the strongest statin?
Rosuvastatin and atorvastatin are the strongest statins because they have long half-lives. – Atorvastatin, simvastatin, and lovastatin are metabolized by the P450 cytochrome 3A4, which is inhibited by many other drugs and may thereby increase the risk of myopathy.
Is atorvastatin an Antihyperlipidemic?
Which of the following is a hypolipidemic agent?
Hypolipidemic drugs are a class of drugs that lower the concentrations of lipoproteins, the agents that transport cholesterol and triglycerides in blood. The lipid-lowering drugs include statins, fibrates, bile-acid sequestrants, and nicotinic acid and acipimox (Xrefer, 2001).