What drugs cause a disulfiram like reaction?
Examples of drugs that have been reported to produce disulfaram-like reactions include metronidazole (Flagyl and other brands), trimethoprim-sulfamethoxazole (Bactrim, Bactrim DS), tinidazole, chlorpropamide (Diabinese), tolbutamide, and others.
What is another name for Antabuse?
Disulfiram
| Clinical data | |
|---|---|
| Trade names | Antabuse, Antabus, others |
| Other names | tetraethyldisulfanedicarbothioamide; 1-(Diethylthiocarbamoyldisulfanyl)-N,N-diethyl-methanethioamide |
| AHFS/Drugs.com | Monograph |
| MedlinePlus | a682602 |
What is the primary purpose of disulfiram?
Generic Name: disulfiram This medication is used along with counseling and support to treat alcoholism. Disulfiram works by blocking the processing of alcohol in the body. This causes you to have a bad reaction when you drink alcohol.
What kind of drug is disulfiram?
Disulfiram is an alcohol antagonist drug. Chemical Name: bis(diethylthiocarbamoyl) disulfide.
How do you treat a disulfiram-like reaction?
Recommended treatment consists of supportive measures such as Trendelenberg posture, administration of oxygen and intravenous infusion of fluid, solute, colloid, and, if needed, a pressor agent such as norepinephrine. Iron salts, ascorbic acid, antihistamines and phenothiazines are of no established benefit.
What are symptoms of a disulfiram type reaction?
Symptoms of this reaction include copious nausea and vomiting, severe headaches, flushing, dizziness, sweating, and chest pain. In some cases, people have experienced trouble breathing, blurry vision, fainting, confusion, and irregular heart rhythms when taking disulfiram with alcohol or alcohol-containing products.
Is Antabuse an antibiotic?
Aims: Disulfiram (Antabuse™) and its metabolites formed in vivo were evaluated as antibacterial agents against thirty species of Gram-positive and Gram-negative bacteria.
Who should not take disulfiram?
severe mental disorder with loss of personality & reality. alcohol intoxication. organic mental disorder. severe disease of the arteries of the heart.
Does Disulfiram make you sleepy?
SIDE EFFECTS: Drowsiness, tiredness, headache, acne, and metallic/garlic-like taste in the mouth may occur as your body gets used to the medication. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
How long does a disulfiram-like reaction last?
The duration of the disulfiram-alcohol reaction varies from 30 to 60 minutes in mild cases to several hours or until the alcohol is metabolized in more severe cases.