How much volume is IVIG?
Among current intravenous products, the newer 10% liquid IVIG formulations can be administered at infusion rates of up to approximately 5 ml/kg/h 74,75 or even 7·2 ml/kg/h 72. For SCIG 16% products, the maximum recommended infusion rates are 10–20 ml/h.
How do you infuse gamunex?
For PI, it is recommended that GAMUNEX-C is infused at a rate of 20 mL per hour per infusion site for adults, and up to 8 infusion sites may be used (most patients used 4 infusion sites)….Administration.
| GAMUNEX®-C vial size | Gauge of needle to penetrate stopper |
|---|---|
| 25, 50, 100, 200, 400 mL | 16 gauge |
How do you administer IVIG infusion?
Initial Dose: Administer intravenously at 15 mg/kg/hr. If no adverse reactions occur after 30 minutes, the rate may be increased to 30 mg/kg/hr; if no adverse reactions occur after a subsequent 30 minutes, then the infusion may be increase to 60 mg/kg/hr (volume not to exceed 75 mL/hr).
How much IVIG should I get?
IVIG doses range from 400 to 800 mg/kg/month are used for immune deficiencies. Doses may be given every three to four weeks. In patients who require auto-inflammatory effects of IVIG, high doses are typically required. This will usually range from 1-2 g/kg as a single dose.
How do you give IVIG in GBS?
Materials and methods: GBS patients being unable to walk unaided are currently treated with a standard single IVIg dose (0.4 g/kg bodyweight for 5 days).
Is gamunex compatible with normal saline?
GAMUNEX (immune globulin intravenous (human) 10%) is not compatible with saline. If dilution is required, GAMUNEX (immune globulin intravenous (human) 10%) may be diluted with 5% dextrose in water (D5/W). No other drug interactions or compatibilities have been evaluated.
Does gamunex C need to be refrigerated?
SHELF LIFE: 36 months in the refrigerator. At room temperature for up to 6 months anytime during the 36-month shelf life, after which the product must be immediately used or discarded. STORAGE REQUIREMENTS: Store in the refrigerator or at room temperature per shelf life.
How fast do you infuse IVIG?
IVIG generally takes about 3 hours for the infusion to be completed. This estimate only includes the time that it takes for the medication to go into your body; it will take additional time to prepare supplies and medications and to place the IV catheter. If your body reacts to the infusion, it will take longer.
Why does IVIG make you tired?
In autoimmune diseases like lupus, the treatment may help your body raise low red-blood-cell counts. Not enough of these and you can become anemic and feel very tired. IVIg helps stop the white blood cells of people with lupus from destroying their red blood cells.
Does IVIG lower immune system?
IVIg can also favorably affect immune system function. It has been proven to be an effective treatment for certain inflammatory diseases such as myositis, a condition where the immune system inappropriately attacks and destroys the muscle cells.
How much Gamunex-C should I take per infusion?
For PI, it is recommended that GAMUNEX-C is infused at a rate of 20 mL/hr per infusion site. In the SC clinical study, the mean volume administered per infusion site was 34 mL (17-69 mL) and the majority of infusions were administered at a rate of 20 mL/hr per site.
Can you use glucose solution with Gamunex 10%?
Gamunex 10% must not be mixed with other solutions for infusion (e.g. saline solution) and other medicinal products. If dilution is necessary prior to infusion, 50 mg/ml glucose solution may be used for this purpose.
Which is the best description of Gamunex-C?
Gamunex-C – Clinical Pharmacology 1 Mechanism of Action. Gamunex-C supplies a broad spectrum of opsonic and neutralizing IgG antibodies against bacteria, viral, parasitic, mycoplasma agents, and their toxins. 2 Pharmacodynamics. Immunoglobulins are fractionated blood products made from pooled human plasma. 3 Pharmacokinetics.
How old do you have to be to take Gamunex C?
GAMUNEX®-C (immune globulin injection [human], 10% caprylate/chromatography purified) is indicated for the treatment of primary humoral immunodeficiency disease (PIDD) in patients 2 years of age and older, idiopathic thrombocytopenic purpura (ITP) in adults and children, and chronic inflammatory demyelinating polyneuropathy (CIDP) in adults.