Can neurofibromatosis cause bladder problems?
Neurofibromatosis type 1 is an autosomal dominant transmitted disease with various clinical manifestations. The bladder is the most commonly affected organ in the genitourinary system.
What is a polypoid lesion in bladder?
Polypoid cystitis is a benign exophytic mucosal lesion of the bladder. Differentiating it from papillary transitional cell carcinoma is difficult due to their similar characteristics.
What is a polypoid bladder mass?
Polypoid cystitis is a rare lesion of the bladder mucosa characterized by inflammation, epithelial proliferation, and development of a polypoid mass without histopathologic evidence of neoplasm. Polypoid cystitis is frequently found in patients with indwelling catheters.
What is neoplasm in bladder?
Bladder neoplasms can arise from any of the bladder layers. They are broadly classified as either epithelial or nonepithelial (mesenchymal), with over 95% being epithelial (,Table 1) (,1). Epithelial tumors with differentiation toward normal urothelium are urothelial.
Does NF1 affect the kidneys?
In about 2% of people with NF1 a defect (called fibromuscular dysplasia) can occur in the tubing of the renal arteries, which causes a narrowing, which causes blood pressure to decrease in that kidney that receives blood from the narrowed artery .
What does polypoid lesion mean?
Any discrete lesion protruding into the lumen of gastrointestinal (GI) tract appeared at endoscopy is called as “polypoid lesion”[3]. However, a polyp is defined as a proliferative or neoplastic lesion of gastrointestinal mucosal layer[3].
What is Malakoplakia?
Malakoplakia is a rare granulomatous disease of infectious etiology that involves the skin and other organs. [1, 2] The name is derived from the Greek malakos (soft) and plakos (plaque), describing its usual clinical presentation as friable yellow soft plaques.
What is benign neoplasm of bladder?
A non-cancerous (benign) tumour of the bladder is a growth that starts in the lining or other tissues of the bladder. A non-cancerous condition is when there is a change to bladder cells. Non-cancerous tumours and conditions do not spread (metastasize) to other parts of the body.
Which is the correct description of bladder exstrophy?
Bladder exstrophy is an abnormality present at birth in which the bladder and associated structures are improperly formed. Rather than being its normal round shape, the bladder is flattened. The skin, muscle and pelvic bones joining the lower part of the abdomen do not form properly so the inside of the bladder is exposed outside the abdomen.
What are the chances of having a child with bladder exstrophy?
Children born to a parent with bladder exstrophy have about a 1 in 70 chance of having it. If a family has one child with this condition, they have a 1 in 100 chance of having another child with it. Fertility treatments may play a role.
What kind of birth defect is the bladder?
Cloacal exstrophy (EC) is a severe birth defect where the abdominal organs (the bladder and intestines) are exposed. The penis or vagina is split, and the anus may be sealed. Mostly, bladder exstrophy occurs as the only birth defect. Spinal cord problems can also occur but are more common with cloacal exstrophy.
Where can I get surgery for bladder exstrophy?
Comprised of expert pediatric urologists from CHOP, Boston Children’s Hospital and Children’s Hospital of Wisconsin, the goal of this multicenter team is to provide expert surgical care of babies born with bladder exstrophy and epispadias. Bladder exstrophy can be repaired with reconstructive surgery.