What is the difference between DCIS and LCIS?
Ductal carcinoma in situ (DCIS), or intra-ductal carcinoma, is breast cancer in the lining of the milk ducts that has not yet invaded nearby tissues. It may progress to invasive cancer if untreated. Lobular carcinoma in situ (LCIS) is a marker for an increased risk of invasive cancer in the same or both breasts.
What is carcinoma in situ neoplasm?
Carcinoma in situ refers to a group of abnormal cells that have not spread from the location where they first formed, although they may later spread into normal tissue and become cancer.
What stage is lobular carcinoma in situ?
Stage 0 means the cancer cells are still within the breast lobule and have not invaded deeper into the surrounding fatty breast tissue. This is called lobular carcinoma in situ (LCIS), a non-invasive breast cancer. In stage 0 cancer, the cancer has not spread to lymph nodes or distant sites.
What are the symptoms of lobular carcinoma in situ?
LCIS doesn’t cause signs or symptoms. Rather, your doctor might discover incidentally that you have LCIS — for instance, after a biopsy to assess a breast lump or an abnormal area found on a mammogram.
Is carcinoma in situ reversible?
Precancer progresses through dysplastic phases to carcinoma in situ and these changes can be documented by aneuploidy in the abnormal cells. Some of all these degrees of dysplasia, including carcinoma in situ, have been shown to be reversible.
What is the best treatment for squamous cell carcinoma in situ?
The simplest and most common treatment for smaller SCC in situ is surgical excision. The standard practice is to remove about a quarter inch beyond the edge of the cancer. Larger ones can also be excised, but Mohs surgery may be needed. It offers the highest cure rate of all treatment methods.
Which is worse lobular or ductal carcinoma?
An analysis of the largest recorded cohort of patients with invasive lobular breast cancer (ILC) demonstrates that outcomes are significantly worse when compared with invasive ductal breast cancer (IDC), highlighting a significant need for more research and clinical trials on patients with ILC.
What are the symptoms of carcinoma in situ?
When ductal carcinoma in situ does produce symptoms, the most common include:
- Breast pain.
- Bloody discharge from the nipple.
- A palpable lump in the breast tissue.
- A red, scaly rash known as Paget’s disease of the breast.
Should I worry about LCIS?
LCIS is not considered to be cancer, and it typically does not spread beyond the lobule (become invasive breast cancer) if it isn’t treated. But having LCIS does increase your risk of developing an invasive breast cancer in either breast later on, so close follow-up is important.
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