What does fluoxetine overdose do?
The majority of fluoxetine overdoses result in a benign clinical course. The largest published case series of fluoxetine overdoses found that the most common effects were tachycardia, drowsiness, tremor, nausea, and vomiting, and concluded that such overdoses typically are “minimally toxic”.
How does prozac make you feel when you first start taking it?
You can feel drowsy in the first few days of taking fluoxetine. However, it should get better after the first week or two. You may become more anxious, or it may make you irritable. This should settle after a couple of weeks.
How does nicergoline work on the cerebral level?
Nicergoline is a potent vasodilator (improves brain blood flow). On the cerebral level it prompts a lowering of vascular resistance, an increase in arterial flow and stimulates the use of oxygen and glucose. Nicergoline also improves blood circulation in the lungs and limbs and has been shown to inhibit blood platelet aggregation.
What is the IC 50 of nicergoline in vitro?
The IC 50 of nicergoline in vitro has been reported to be 0.2 nM. The primary action of nicergoline is to increase arterial blood flow by vasodilation. Furthermore, it is known that nicergoline inhibits platelet aggregation.
Are there any side effects to taking nicergoline?
Adverse effects. The side effects of nicergoline are usually limited to nausea, hot flushes, mild gastric upset, hypotension and dizziness. At high dosages bradycardia, increased appetite, agitation, diarrhea and perspiration have been known to occur.
What kind of diseases can nicergoline be used for?
It is used for vascular disorders such as cerebral thrombosis and atherosclerosis, arterial blockages in the limbs, Raynaud’s disease, vascular migraines, and retinopathy . Nicergoline has been registered in over fifty countries and has been used for more than three decades for the treatment of cognitive, affective,…