Can ITP affect pregnancy?
A diagnosis of the autoimmune disease ITP may change many things about your life, but fortunately it doesn’t prevent you from becoming pregnant—or having a perfectly healthy baby.
Does low platelets in pregnancy affect baby?
The baby is unlikely to develop low platelets if your decreased count is caused by regular dips in pregnancy or hypertension. However, if your low count is due to an immune condition, the antibodies that destroy platelets may cross the placenta and cause the same issues for the fetus.
How does pregnancy cause ITP?
The pathophysiology of gestational thrombocytopenia is unknown, but 2 main factors are associated with GT. Accelerated platelet activation is suspected to occur at placental circulation. Accelerated consumption of platelets is due to the reduced lifespan of platelets during pregnancy.
Can you give birth with ITP?
Having ITP should not prevent women from becoming pregnant or delivering a healthy child. The vast majority of women with pre-existing ITP will have a successful pregnancy, but closer monitoring and sometimes treatment is needed to ensure the best outcome.
How is ITP treated during pregnancy?
IVIg and low-dose corticosteroids comprise the mainstays of treatment in ITP, but high doses of corticosteroids or prolonged corticosteroid therapy are associated with significant toxicity in the pregnant patient and should be avoided.
Can ITP cause miscarriage?
Results suggest that women diagnosed with ITP or cITP prior to their estimated date of conception may be at higher risk for stillbirth, fetal loss, and premature delivery. Among 446 pregnancies in women with ITP, 346 resulted in live births.
How does ITP diagnose pregnancy?
The presentation of ITP in pregnancy is much like that in the non-pregnant individual. Patients may be diagnosed following the detection of asymptomatic thrombocytopenia on routine testing, or less commonly with more severe thrombocytopenia accompanied by bruising, bleeding, and petechiae.
What can cause low platelet count in pregnancy?
Gestational thrombocytopenia (defined as a mild thrombocytopenia, occurring during the 3 rd trimester with spontaneous resolution postpartum and no neonatal thrombocytopenia) is the most common cause of thrombocytopenia during pregnancy but a low platelet can also be associated with several diseases, either pregnancy …
How much platelet count is normal in pregnancy?
There is a normal drop in platelet count during pregnancy. In the first trimester, the normal count is around 250,000 and decreases to about 225,000 at delivery. Platelet counts <100,000 were rarely encountered in normal, uncomplicated pregnancies and should not generally be considered a physiologic change.