What is Adenomyoma of gallbladder?
Abstract. Gallbladder (GB) adenomyomatosis (ADM) is a benign, acquired anomaly, characterized by hypertrophy of the mucosal epithelium that invaginates into the interstices of a thickened muscularis forming so-called Rokitansky-Aschoff sinuses. There are three forms of ADM: segmental, fundal and more rarely, diffuse.
Is Adenomyomatosis of the gallbladder cancerous?
Originally recognized as a precancerous lesion, adenomyomatosis is currently recognized by recent studies as a benign alteration of the gallbladder that is often associated with cholecystitis and cholecystolithiasis. Gallbladder carcinoma is an extremely malignant disease with a 5-year survival rate of less than 5%.
What are the symptoms of gallbladder adenomyomatosis?
The most common presentation of GAM is pain in the upper right quadrant of the abdomen, which is similar to gallstone pain with or without cholecystitis. This pain is intermittent and mostly self-limiting [5,6]. It is possible that GAM symptoms are secondary to gallstones and inflammation.
Does gallbladder adenomyomatosis require surgery?
Symptomatic adenomyomatosis is considered an indication for cholecystectomy, while asymptomatic disease is not an indication for surgery. If there is any clinical or radiological doubt about the possibility of adenocarcinoma of the gallbladder, a cholecystectomy is usually warranted [7].
What is a Adenomyoma?
Adenomyoma of the uterus is a circumscribed nodular aggregate of benign endometrial glands surrounded by endometrial stroma with leiomyomatous smooth muscle bordering the endometrial stromal component. It may be located within the myometrium, or it may involve or originate in the endometrium and grow as a polyp.
What color is gallbladder sludge?
Gallbladder sludge is a collection of cholesterol, calcium, bilirubin, and other compounds that build up in the gallbladder. It is sometimes called biliary sludge because it occurs when bile stays in the gallbladder for too long. Bile is a greenish-yellow fluid that produced in the liver and stored in the gallbladder.
What causes gallbladder Adenomyomatosis?
It occurs as a result of poorly understood hyperplastic changes involving the mucosa and muscular wall of the gallbladder and the formation of intramural sinuses, known as the Rokitansky-Aschoff sinuses, which are characteristic of this disease. Involvement of the gallbladder may be diffuse or segmental.
What causes Adenomyomatosis of gallbladder?
Adenomyomatosis is caused by an overgrowth of the mucosa, thickening of the muscular wall, and formation of intramural diverticula or sinus tracts termed Rokitansky–Aschoff sinuses, also called entrapped epithelial crypts.
Is adenomyoma a tumor?
Endocervical adenomyoma is classically a well-demarcated biphasic tumor with glands set in a stroma composed of predominantly smooth muscle arranged in fascicles. The glands, which are lined by benign endocervical type mucinous epithelium, are cystic or irregularly shaped, and exhibit a somewhat lobular growth pattern.
How is adenomyoma treated?
The only definitive cure for adenomyosis is a hysterectomy, or the removal of the uterus. This is often the treatment of choice for women with significant symptoms.
How reliable is ultrasound to detect gallstones?
Ultrasound is about 98% accurate in detecting gallstones, hard, pebble-like deposits that form in the gallbladder, the organ just below your liver. Ultrasound is a painless, noninvasive procedure that uses sound waves to project an image of interior body parts up on a screen.
What is Adenomyomatosis of gallbladder?
Adenomyomatosis is a common tumorlike lesion of the gallbladder with no malignant potential and may involve the gallbladder in a focal, segmental, or diffuse form. The focal type is the most common and usually involves the gallbladder fundus. Differentiating between adenomyomatosis and cholesterolosis is difficult at times.
What is a thick gallbladder wall?
Thickening of the gallbladder wall is a relatively frequent finding at diagnostic imaging studies. A thickened gallbladder wall measures more than 3 mm, typically has a layered appearance at sonography [1], and at CT frequently contains a hypodense layer of subserosal oedema that mimics pericholecystic fluid [2]