What is hepatic Hemangioendothelioma?
Hepatic epithelioid hemangioendothelioma (EHE) is a very rare malignant vascular tumor composed of epithelioid and histiocytoid endothelial cells in a myxohyaline or fibrous stroma. It may also occur in the lungs, soft tissue and bone. Primary hepatic hemangioendothelioma was first reported by Ishak et al. in 1984 [1].
Is Hemangioendothelioma malignant?
Background. Epithelioid hemangioendothelioma (EHE) is a rare malignant vascular neoplasm with increasing incidence. However, its clinical characteristics remain unclear due to its low incidence.
What causes Hemangioendothelioma?
Hemangioendotheliomas are caused by abnormal growth of blood vessel cells , although the exact underlying cause for the abnormal growth is unknown. They can also develop in an organ , such as the liver or lung. They usually grow slowly and can sometimes spread to other tissues in the body (metastasize).
What does Hemangioendothelioma look like?
These tumors are so named because their histologic appearance resembles a proliferation of epithelioid cells, with polygonal shape and eosinophilic cytoplasm. Composite hemangioendothelioma is a low-grade angiosarcoma typically occurring in adults, although it has been described in infancy.
What causes hemangioendothelioma?
What is Kaposiform Lymphangiomatosis?
Kaposiform lymphangiomatosis (KLA) is a rare type of tumor and vascular malformation that results from the abnormal development of the lymphatic system . The lymphatic system is part of the immune system made up of vessels that help to protect the body from infection and foreign substances.
What are the physical signs of infantile hemangiomas?
Infantile hemangiomas exhibit a characteristic evolution, with early rapid growth (proliferation) followed by slow involution. [ 1] The earliest sign of a superficial infantile hemangioma is blanching of the involved skin. This may be followed by fine telangiectasias and then a red or crimson macule.
How common are infantile hemangiomas?
Hemangiomas (Infantile) Hemangiomas of infancy are benign (noncancerous) vascular tumors composed of cells that normally line the blood vessels (endothelial cells). They are the most common tumor of childhood, occurring in up to 10 percent of infants. Hemangiomas are seen in all racial groups but are more common in Caucasians .
What are the clinical features of hepatic hemangiomas?
In most cases, a liver hemangioma doesn’t cause any signs or symptoms. When a liver hemangioma causes signs and symptoms, they may include: Pain in the upper right abdomen Feeling full after eating only a small amount of food
What is a deep hemangioma?
Deep hemangiomas grow under the skin, making it bulge, often with a blue or purple tint. Deep hemangiomas are also called subcutaneous (“under the skin”) hemangiomas. Hemangiomas also may develop in organs inside the body, such as the kidneys, lungs, liver, or brain, where they can’t be seen.