What is the drug lamivudine used for?
Lamivudine (Epivir-HBV) is used to treat hepatitis B infection. Lamivudine is in a class of medications called nucleoside reverse transcriptase inhibitors (NRTIs). It works by decreasing the amount of HIV and hepatitis B in the blood.
What is the generic for lamivudine?
Lamivudine oral tablet is available as a generic drug and a brand-name drug. Brand name: Epivir, Epivir-HBV.
When should I take lamivudine tablets?
The combination of lamivudine and zidovudine comes as a tablet to take by mouth. It is usually taken twice a day with or without food. Take lamivudine and zidovudine at around the same times every day.
What is abacavir and lamivudine for?
The combination of abacavir, lamivudine and zidovudine is used alone or along with other medications to treat human immunodeficiency virus (HIV) infection. Abacavir, lamivudine and zidovudine are in a class of medications called nucleoside reverse transcriptase inhibitors (NRTIs).
Is Lamivudine an antiviral?
Lamivudine, commonly called 3TC, is an antiretroviral medication used to prevent and treat HIV/AIDS. It is also used to treat chronic hepatitis B when other options are not possible. It is effective against both HIV-1 and HIV-2….Lamivudine.
| Clinical data | |
|---|---|
| PubChem CID | 60825 |
| DrugBank | DB00709 |
| ChemSpider | 66068 |
| UNII | 2T8Q726O95 |
Can I take Arvs in the morning?
Taking it at night means you are sleeping and avoiding some of the side effects. If you are on a combination that oddest contain efavirenz it should be ok to take int the morning. The important thing is that you continue to take your medication at the same time every day.
Can lamivudine cause kidney problems?
Several case reports describe potential nephropathy (including Fanconi syndrome) secondary to administration of abacavir, didanosine, lamivudine and stavudine. Case reports documented renal events such as acute renal failure, nephritis, proteinuria and renal stones with efavirenz administration.
What is lamivudine side effect?
Lamivudine is generally a safe drug, with fewer side effects than other nucleoside reverse transcriptase inhibitors (NRTIs). Its most common side effects are headache, fatigue, and nausea which generally subside over time. Other side effects include decreased appetite, diarrhoea, skin rash, and abdominal pain.
Who should not take lamivudine?
If you have or have had liver problems, including hepatitis B virus infection (HBV) or hepatitis C virus infection (HCV). If you have kidney problems. If you have diabetes. Each 15-mL dose (150 mg) of lamivudine oral solution contains 3 grams of sucrose (common table sugar).
Is lamivudine the same as abacavir?
Abacavir and lamivudine both belong to a class of drugs known as nucleoside reverse transcriptase inhibitors (NRTIs). Abacavir/lamivudine is not a cure for HIV infection.
What is Efavirenz 600mg?
Efavirenz is used along with other medications to treat human immunodeficiency virus (HIV) infection. Efavirenz is in a class of medications called non-nucleoside reverse transcriptase inhibitors (NNRTIs). It works by decreasing the amount of HIV in the blood.
What class drug is lamivudine?
Lamivudine belongs to a class of drugs known as nucleoside reverse transcriptase inhibitors-NRTI. Lamivudine is not a cure for HIV infection.
What kind of action does lamivudine have on HBV?
Lamivudine is a synthetic nucleoside analogue with activity against hepatitis B virus (HBV) and HIV. Intracellularly, lamivudine is phosphorylated to its active metabolites, lamiduvine triphosphate (L-TP) and lamiduvine monophosphate (L-MP).
How does lamivudine inhibit the reverse transcriptase of HIV?
It can inhibit both types (1 and 2) of HIV reverse transcriptase and also the reverse transcriptase of hepatitis B virus. It is phosphorylated to active metabolites that compete for incorporation into viral DNA. They inhibit the HIV reverse transcriptase enzyme competitively and act as a chain terminator of DNA synthesis.
What are the side effects of long term use of lamivudine?
Long-term use of lamivudine can trigger a resistant hepatitis B virus (YMDD) mutant. HIV or HBV-infected women on lamivudine are warned to discontinue breastfeeding as this puts the baby at risk for HIV transmission and medication side effects. Patients who are infected with HIV and HCV and are on both interferon…
How is lamivudine metabolite incorporated into viral DNA?
Lamivudine is a synthetic nucleoside analogue and is phosphorylated intracellularly to its active 5′-triphosphate metabolite, lamivudine triphosphate (L-TP). This nucleoside analogue is incorporated into viral DNA by HIV reverse transcriptase and HBV polymerase, resulting in DNA chain termination.