What is inactivation in biology?
Inactivation occurs when RNA transcribed from the Xist gene on the X chromosome from which it is expressed spreads to coat the whole X chromosome. Before the signal that initiates random X-chromosome inactivation is received, Xist and Tsix are transcribed from all active X chromosomes in each male and female cell [6].
What is cell inactivation?
Abstract. The inactivation of cells resulting in lethal or aberrant effects by charged particles is of growing interest. Charged particles at extremely high LET are capable of completely eliminating cell-type and cell-line differences in repair capacity.
Is it inactivate or deactivate?
As verbs the difference between inactivate and deactivate is that inactivate is to make inactive while deactivate is (ergative) to make something inactive or no longer effective.
What is bacterial inactivation?
Pathogen inactivation: A process designed to eliminate pathogens from water, air or donated blood. Pathogens include viruses, bacteria, and fungi. One form of pathogen inactivation for blood uses a chemical that, when exposed to ultraviolet light, binds to the genetic material.
What is gene inactivation?
Gene inactivation can be achieved by applying the nuclease only and allowing the error-prone nonhomologous end-joining pathway to introduce nested insertions and deletions at the cleavage site, disrupting the gene sequence.
What is Lyonization in zoology?
Lyonization = Lyonization is commonly known as X-inactivation. In mammals, males receive one copy of the X chromosome while females receive two copies. To prevent female cells from having twice as many gene products from the X chromosomes as males, one copy of the X chromosome in each female cell is inactivated.
How do genes escape inactivation?
In mammals, sex chromosomes pose an inherent imbalance of gene expression between sexes. In each female somatic cell, random inactivation of one of the X-chromosomes restores this balance. While most genes from the inactivated X-chromosome are silenced, 15–25% are known to escape X-inactivation (termed escapees).
Is Disactivate a word?
New Oxford American Dictionary doesn’t contain the word either. Google Books Ngram Viewer shows no mentions of “disactivate”. You should use “deactivate” instead of “disactivate”. Dictionnaries have not always all the words we use or need, as there are sedimentations of common vocab.
Is deactive a word?
Definitions for deactive. de·ac·tive.
How do you inactivate pathogens?
Solvent detergent pathogen reduction of plasma is the most widely studied methodology and is currently in use across Europe. Other methods include photosensitizing chemicals that interact with pathogen DNA and/or RNA and cross-link following exposure to UVA or visible light, thus inactivating the nucleic acids.
How do you inactivate bacteria?
Inactivation of bacteria: To inactivate the bacterial cells and preserve their surface structures, different fixation methods have been demonstrated. Inactivation by chemical agents [47], heat [48], sonication [49] and UV irradiations [50, 51] are of these methods.
Which is the best definition of inactivation?
/in·ac·ti·va·tion/ (in-ak″tĭ-va´shun) the destruction of biological activity, as of a virus, by the action of heat or other agent.
What does it mean to inactivate a virus?
— NBC News, 10 Dec. 2020 To inactivate the virus, researchers disable the genetic components that are normally responsible for making the virus replicate inside a body. — Amanda Morris, The Arizona Republic, 5 Dec. 2020
What does it mean when a gene is inactive?
Most of the genes on the Barr body are inactive, meaning that they are not transcribed. The process of X-inactivation was discovered by the British geneticist Mary F. Lyon and is sometimes called lyonization in her honor. Photograph of Mary F. Lyon, discoverer of X-inactivation.
How is the inactivation of an enzyme enhanced?
Inactivation is strongly enhanced by gas bubbling for the three studied enzymes, lysozyme, lipase and pectinmethylesterase. Nitrogen bubbling in an enzyme solution generates irreversibly inactivated enzyme molecules.